Imaging expertise at every stage of your trial
Engage us for a single phase or the full programme. Every service is tailored to your study and developed with your clinical team and CRO.
Your whole imaging study, in one lockable case
Every site receives an identical, ready-configured kit. It runs the behavioural tasks, presents stimuli in the scanner and sends imaging and task data back to us automatically and securely. Sites plug in and start scanning; we keep everything up to date remotely.
What's in the box
- Touchscreen study laptop for behavioural testing and in-scanner stimulus presentation
- Scanner trigger and button-box connections for precisely timed fMRI tasks
- Built-in cellular connectivity for secure upload, updates and remote support
- USB key for moving scanner data to the kit
- Your study's task battery, pre-installed and configured
How it works at the site
- 1Run behavioural tasks with the participant on the touchscreen.
- 2Connect to the scanner and present the fMRI tasks; responses come in via the button box.
- 3Plug in the USB key with the scan data. The kit processes and uploads everything automatically.
- 4We run quality control and report back promptly.
Why sponsors choose it
- Comparable data across centres and countries
- Faster site start-up, with no local software to install
- GDPR- and HIPAA-compliant encrypted data transfer
- Timely QC, because data arrives as soon as it is collected
- Remote fixes and task updates, without site visits
Pre-trial consultancy
Designing imaging into the study so it can answer the clinical question, with protocols that work across your sites.
Choosing imaging endpoints that are sensitive to your intervention.
Sequence and hardware advice from acquisition specialists.
Protocols balanced for data quality, scan time and patient burden.
Tuning parameters for the analyses you plan to run.
Imaging study support
Keeping data consistent and usable across every site, for the whole life of the study.
Confirming each scanner can deliver the protocol.
Minimising scanner and site effects in multi-centre data.
Catching problems early with rapid feedback to sites.
Agreed formats and routes between sites, CRO and us.
Hands-on training and study-specific imaging manuals for site staff.
Data analysis
Pre-specified, validated outcome measures, delivered to agreed timelines and formats.
A priori imaging endpoints aligned with your hypotheses.
Imaging SAPs written and agreed before unblinding.
Semi-automated QC on every scan, billed separately.
Integrated functional, structural and behavioural analysis.
Post-trial interpretation
Turning imaging biomarkers into a clear account of clinical outcome.
What the imaging findings mean for your programme.
Help preparing results for peer-reviewed dissemination.
Hardware and software support for every scanner
From the first site visit to the last participant, we help each centre collect consistent, high-quality data.
Protocol installation on the scanner, operator training and study-specific imaging manuals.
Phantom and volunteer scans to catch hidden scanner issues before the first participant.
Regular phantom QA and prompt quality feedback on every session uploaded.
Secure, encrypted data transfer solutions that meet European and US privacy requirements.
Ready-to-deploy task fMRI, at every site
Task fMRI shows how a treatment changes the brain circuits behind reward, inhibition, memory and emotion. Our battery of validated paradigms comes in matched behavioural and in-scanner versions, delivered to sites ready to run on Study in a Box, and analysed alongside structural and resting-state measures. When your study needs something new, we implement custom, dedicated tasks.
Reward and motivation
- Monetary Incentive Delay (MID)
- Social Incentive Delay (SID)
- Food reward sensitivity and cue reactivity
- Delay Discounting (DDT)
- Effort-for-reward tasks
- Probabilistic and reversal learning
Impulsivity and inhibition
- Go/No-Go, including affective variants
- Stop-Signal Task (SST)
- 4-Choice Serial Reaction Time Task
Cognition and memory
- N-Back working memory
- Digit Symbol Substitution
- Verbal memory: encoding, recall and recognition
Emotional and social processing
- Facial expression recognition
- Emotional categorisation, recall and memory
- Face dot-probe attention bias
- Empathy and social value orientation
Outcome measures across every MR modality
Structural MRI
- Tissue-type and sub-cortical segmentation
- Voxel-wise grey-matter density
- Longitudinal atrophy, accurate to 0.2% brain volume change, with skull-based correction for scanner drift
- Automated T2-FLAIR lesion segmentation (BIANCA)
Functional MRI
- State-of-the-art denoising, including ICA-AROMA
- Resting-state network maps and amplitude
- Functional connectivity matrices and graph-theory measures
- Task fMRI from our ready-to-deploy battery: subject-level GLM to group models
Diffusion & perfusion
- White-matter microstructure
- Tractography and structural connectivity
- Arterial spin labelling: absolute and relative cerebral blood flow
- Pharmacological challenge designs
Results in the form your team needs
Not sure which services you need?
Tell us about your study and we will suggest the right level of support.